A case of cytomegalovirus pneumonitis in a patient with systemic lupus erythematosus.
- Author:
Dae Ho LEE
1
;
Jin Wook KIM
;
Dong Hyun SHIN
;
Myoung Don OH
;
Yeung Wook SONG
;
Kang Won CHOI
;
Jung Sang LEE
Author Information
1. Department of Internal Medicine, College of Medicine Seoul National University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
CMV pneumonitis;
systemic lupus erythematosus
- MeSH:
Anoxia;
Biopsy;
Cyclophosphamide;
Cytomegalovirus*;
Diagnosis;
Dyspnea;
Female;
Fever;
Ganciclovir;
Humans;
Immunization, Passive;
Lung;
Lung Diseases, Interstitial;
Lupus Erythematosus, Systemic*;
Pneumonia*;
Prednisolone;
Thorax;
Ventilators, Mechanical;
Young Adult
- From:Korean Journal of Medicine
1999;56(1):103-107
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of cytomegalovirus(CMV) pneumonitis in a 21-year-old woman with systemic lupus erythematosus(SLE). She was diagnosed 3 years ago with lupus nephropathy and was on immunosuppressive therapy with prednisolone and cyclophosphamide. She developed dyspnea with fever and hypoxemia. Chest X-ray, and HRCT showed interstitial pneumonitis. We performed open lung biopsy. The diagnosis of CMV pneumonitis was made by the virus culture and immunohistochemical staining for CMV in lung tissue. Despite the admini stration of ganciclovir and high dose immunoglobulin therapy and assistance of mechanical ventilator, the patient died.
