Treatment of chronic allograft dysfunction with mycophenolate mofetil after kidney transplantation:a multicenter study
- VernacularTitle:霉酚酸酯治疗慢性移植物功能减退的多中心研究
- Author:
Wujun XUE
;
Hang YAN
- Publication Type:Journal Article
- Keywords:
Renal transplantation;
Mycophenolate mofetil;
Chronic allograft dysfunction
- From:
Chinese Journal of Organ Transplantation
1996;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the therapeutic effectiveness and safety of mycophenolate mofetil (MMF) in the treatment of chronic allograft dysfunction (CAD).Methods Seventy-eight patients with CAD were administrated with MMF substituting for Aza or CTX with concomitant low-dose CsA. The effectiveness and complications were analyzed. The mean follow-up time after MMF treatment was 9.48 months.Results After treatment with MMF in combination with low doses of CsA and Pred,the serum creatinine concentration (SCr) in 74 CAD patients was significantly decreased and remained stable at the end of follow-up ( P