Study of Positron Emission Tomography Scanning Image of Alzheimer's disease with SPM Software
- VernacularTitle:统计参数图软件对Alzheimer病患者脑PET图像的初步分析
- Author:
Kaida JIANG
;
Qiuyun CAO
;
Baoci SHAN
;
Xiuli YUAN
;
Mingyuan ZHANG
;
Shifu XIAO
;
Chuantao ZUO
;
Hongfang HUA
;
Yongchang LIU
- Publication Type:Journal Article
- Keywords:
Alzheimer disease;
Positron emission tomography,
- From:
Chinese Journal of Geriatrics
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the feature of regional cerebral metabolism rate of glucose (rCMRglc) in patients with Alzheimer’s disease (AD) and the value of positron emission tomography (PET) scanning in diagnosis of AD. Methods 13 AD patients and 13 health controls ,Who matched in age,sex and education years,were scanned with PET. Results (1) Watching by naked eyes,there was mild decreasing of rCMRglc at parietal lobe in healthy elders. While in AD patients,there was widely decreasing of cerebral metabolism rate of glucose. The most significant region was parietal lobe, the next was temporal lobe,and the last was frontal lobe. (2) Detecting with PET and dealing with statistical parametric mapping (SPM) of 99 software,there was more significant decreasing of rCMRglc in regions 7,23,30,31 of cingulate gyrus,region 39 and 40 of pario-occipital lobe,region 20 of temporal lobe and region 6,8,9 of frontal lobe in AD group( P
