Relation between antidiuretic hormone and nocturnal polyuria in patients with spinal cord injury

VernacularTitle:脊髓损伤患者夜间尿量增多与抗利尿激素水平的关系
Author: Decheng WANG ; Zhenshan YU ; Yakui ZHANG ; Xueming CHEN ; Tao GUO ; Hui CHEN ; Hua GUAN
Publication Type:Journal Article
Keywords: Spinal cord injuries; Antidiuretic hormone,inappropriate secretion; Urination disorders; Osmotic pressure; Blood pressure
From: Chinese Journal of Trauma 2003;0(07):-
CountryChina
Language:Chinese
Abstract: Objective To evaluate the relationship of diurnal variation of antidiuretic hormone (ADH) with urinary output,serum osmolality and blood pressure in spinal cord injury (SCI) patients. MethodsThe study was prospective,random and contrastive. Twenty complete SCI patients (two females and 18 males,Complete SCI group) and ten healthy controls (two females and eight males,control group) were studied. Urinary output and osmolality in the day time (8:00-20:00) and at night (20:00-8:00) were recorded. Blood samples for the measurement of serum osmolality and ADH were drawn at 14:00 and 2:00. Results There was very significant difference in regard of urinary output between day time and night time in complete SCI Group and control Group ( P 0.05). However,ADH level increased in the healthy Group at night,with a very significant difference ( P