Treatment of 34 cases of non small cell lung cancer in the elderly patients using vinorelbine and oxaliplatin
- VernacularTitle:长春瑞滨联合奥沙利铂治疗34例老年非小细胞肺癌
- Author:
Daogen YAO
;
Linfang ZHOU
;
Jiao SHEN
- Publication Type:Journal Article
- Keywords:
vinorelbin;
oxaliplati;
non small cell lung cancer(NSCLC);
combined chemotherapy
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To investigate the effects on non small cell lung cancer(NSCLC) and untoward reactions in elderly patients using vinorelbine(NVB) and oxaliplatin. Methods:NVB 25mg/m 2 ivgtt on day 1 and 8,oxalipatin 85mg/m 2 ivgtt on day 1 and 8, at 21 days per cycle. And every case should receive at least 2 cycles. Results:Among 34 patients,complete response(CR):2.9%,partial response(PR):35.3%,stable disease(SD):44.1%,progressive disease(PD):17.6%.Total response rate(RR) is 38.2%. The side effects were myelosuppression and peripheral sensory nueropathy. Conclusions:NVB combined with oxaliplatin treating NSCLC in elderly people has some effect,and the toxixity can be well tolerated.
