Study on polymorphisms of mitochondrial DNA D-loop region in the Sala population in China
- VernacularTitle:中国撒拉族线粒体DNA序列遗传多态性研究
- Author:
Xinshe LIU
;
Shengbin LI
- Publication Type:Journal Article
- Keywords:
mtDNA;
sequence polymorphism;
D-loop region
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the mitochondrial DNA sequence polymorphisms in the Sala population from northwest China and to provide basic data for forensic purpose. Methods Genomic DNA was extracted from the whole blood of 100 unrelated individuals of the Sala population. The sequence polymorphic locus was determined by direct sequencing. Results 83 loci were observed in mtDNA np16 091-16 418 region, and 75 haplotypes were confirmed. The genetic diversity was estimated to be 0.991 2, and the random match probability was calculated to be 0.018 9. Conclusion There are some particular polymorphic loci in the Sala population. The results suggest that there are different genetic structures between Chinese and other Asian population in mitochondrial DNA D-loop region; mitochondrial DNA sequence polymorphism np16 091-16 418 can be used as a genetic marker for forensic individual identification.
