Subgenotype Analysis of Hepatitis C Virus in paid Biood Donors
- VernacularTitle:个体供血者丙型肝炎病毒基因亚型分析
- Author:
Zuhu HUANG
- Publication Type:Journal Article
- Keywords:
Paid blood donors;
Hepatitis C virus;
Subgenotype
- From:
Chinese Journal of Blood Transfusion
1988;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The detecting of HCV-RNA and genotyping of HCV in sera of 65 paid blood donors which are positive for anti-HCV were conducted,indicating that 60 of them appeared positive for HCV-RNA,and their genotype of HCV was classified as genotype- I . It was suggested that the genotype- I of HCV could be considered as the predominant infectious strain in this group of paid blood donors. It was found that the endonuclease digestion method of typing based on HCV 5' -noncoding region PCR was better compared with the direct method of typing based on HCV core region PCR in terms of its senstivity,economy and simplicity.