The effects of the cardiopulmonary bypass temperature on somatosensory cortical evoked potential and super microstructure of cortex in rabbit
- VernacularTitle:不同温度体外循环对兔皮层超微结构和体感皮层诱发电位的影响
- Author:
Jianjun MA
- Publication Type:Journal Article
- Keywords:
Cardiopulmonary Bypass;
Temperature;
Somatosensory Cortical Evoked Potential;
Super microstructure
- From:
Journal of Chongqing Medical University
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The objective of this study is to detect the effects of normothermic,mild hypothermic,hypothermic cardiopulmonary bypass(CPB) on somatosensory,cortical evoked potential(SCEP) and super microstructure of cortex in rabbits. Methods:Thirty new zealand white rabbits,randomly allocated into three groups;group A:normothermia CPB(36℃~37℃); group B:mild hypothermia CPB (32℃~34℃);group C:hypothermia CPB (26℃~28℃);Made the open-heart CPB model, maintaining HCT 20%~25%,the duration of CPB is 2 hours;Stimulating from ischiadic nerve,recording SSEP by the time of the end of CPB,The animals were then killed and the cortex were removed for electro microscopic examination.Results:The latency of group C is longer than group B,the latency of group B is longer than the group A,compare between each group (P