Insulin resistance of islet cells: the central role of pathogenesis in type 2 diabetes?
- VernacularTitle:胰岛细胞胰岛素抵抗:2型糖尿病发病机制的主角?
- Author:
Jiawei ZHAO
;
Xiujun LI
- Publication Type:Journal Article
- Keywords:
Insulin resistance, ? cell;
Insulin resistance, peripheral;
Diabetes mellitus, type 2
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Systemic insulin resistance has been well known. Recently, an important question has been raised regarding whether islet cells are resistant to insulin (insulin resistance of ?, ? and ? cells) due to the discovery of insulin receptor and its downstream insulin signaling pathways in islet cells. As a new study field of insulin resistance, the elucidation to this issue is crucial for the new insight into the mechanisms of insulin resistance per se and type 2 diabetes.
