Association between islet cell antibody subtypes and secretions of insulin and glucagon
- VernacularTitle:胰岛细胞抗体亚型与胰岛素、胰高血糖素分泌的关联
- Author:
Yali AN
;
Guangwei LI
;
Xueli LIU
;
Lin PAN
- Publication Type:Journal Article
- Keywords:
Islet cell antibodies;
Insulin;
Glucagon;
Latent autoimmue diabetes of adult
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the insulin and glucagon levels in the patients with different islet cell antibody (ICA) subtypes and to explore the pathogenesis of latent autoimmune diabetes of adult (LADA). Methods Subjects were classified by immunohistology and 29 ICA-peripheral-positive DM patients, 28 ICA-diffused-positive DM patients and 17 controls (ICA-negative) were included. Serum glucose, insulin and plasma glucagon were measured at 0, 30, 60, 120 min after standard meal. Results (1) As compared with controls, glucagon in ICA positive groups were higher (both P
