Correlation between single nucleotide polymorphism of adiponectin gene and type 2 diabetes in Chinese
- VernacularTitle:中国人脂联素基因单核苷酸多态性与2型糖尿病的相关性
- Author:
Hui XIA
;
Yongzhen MO
;
Rongwen BIAN
;
Jie SHEN
;
Lijun MA
- Publication Type:Journal Article
- Keywords:
Adiponectin;
Gene;
Polymorphism, single nucleotide;
Diabetes mellitus, type 2
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Two single nucleotide polymorphisms (SNP) of adiponectin gene (SNP+45 and SNP+276) were screened in Chinese population. The results showed that the distribution of SNP+45 genotypes were significantly different and G/G genotype in type 2 diabetic population appeared more frequently than that in non-diabetic population. It suggests that adiponectin gene seems to be the susceptive gene in Chinese type 2 diabetics.
