Dynamic alteration of gene expression of the platelet-derived growth factor on SAH with late responseive cerebral vasospasm in rat
- VernacularTitle:大鼠蛛网膜下腔出血迟发性脑血管痉挛血小板衍生生长因子基因表达动态变化
- Author:
Jun WU
;
Haiou ZHANG
;
Chunkui ZHOU
;
Mingli RAO
- Publication Type:Journal Article
- Keywords:
Subarachnoid hemrnhage;
Vasospasm, intracranial
- From:
Chinese Journal of Geriatrics
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of platelet-derived growth factor(PDGF) in DCVS diseases after SAH. Methods Alteration of PDGF gene and mRNA expression in DCVS brain tissues after SAH by RT-PCR and immunohistochemistry. Results To compare with the control group, transcription level of PDGF mRNA up-regulated evidently 3 days after transfusion (P