Regional Citrate Anticoagulation in Continuous Venovenous Hemodiafiltration: Report of Two Cases.
- Author:
Jun Am SHIN
1
;
Yong Sung CHOI
;
Hae Won JUNG
;
Yu Ji LEE
;
Na Ree KANG
;
Sun YANG
;
Tae Kyu LIM
;
Jung Eun LEE
;
Wooseong HUH
;
Dae Joong KIM
;
Ha Young OH
;
Yoon Goo KIM
Author Information
1. Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ygkim@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Continuous renal replacement therapy;
Heparin;
Regional citrate anticoagulation
- MeSH:
Calcium;
Citric Acid*;
Critical Illness;
Hemodiafiltration*;
Hemorrhage;
Heparin;
Humans;
Renal Insufficiency;
Renal Replacement Therapy
- From:Korean Journal of Nephrology
2006;25(3):447-451
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Continuous renal replacement therapy (CRRT) has been used increasingly for the management of renal failure in hemodynamically unstable and critically ill patients. CRRT requires anticoagulation, usually with heparin, to prevent clotting in the extracorporeal circuit. Systemic heparinization is associated with a high rate of bleeding when used during CRRT in critically ill patients. We applied regional citrate anticoagulation for CRRT to two critically ill patients with high bleeding risk using calcium containing commercial solutions. We conclude that regional citrate anticoagulation with commercial calcium containing solution can be used alternative to heparin for CRRT in patients with high bleeding risk.
