Influence of initial periodontal therapy on the presence of oral Helicobacter pylori and the relation of genotype of Helicobacter pylori in oral cavity and with that in stomach
- VernacularTitle:牙周基础治疗对口腔幽门螺杆菌的影响及其基因型关系的研究
- Author:
Hailing HOU
;
Huanxin MENG
;
Fulian HU
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Dental plaque;
Periodontitis;
Polymerase chain reaction;
Genotype
- From:
Journal of Practical Stomatology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate whether initial periodontal therapy may affect the presence of oral Helicobacter pylori(Hp), and to compare the genotype of Helicobacter pylori in oral cavity and that in stomach. Methods: 56 patients with gastric Hp and periodontitis were enrolled in this study. PCR was carried out to identify the presence of Hp in the samples before and after initial periodontal therapy(group 1) or medicine therapy(group 2). DNA sequence of PCR products of 5 patients and 1 Hp infected patient's relative was compared and analyzed. Results: Four weeks after medicine therapy, the rate of Hp in oral cavity was singnificantly lower in group 1 than that in group 2 (3.0% vs 26.1%, P