Significance of systolic peak velocity index combined with dipyridamole stress echocardiography on study of acute myocardial ischemia
- VernacularTitle:双嘧达莫负荷组织速度成像技术在急性心肌缺血研究中的意义
- Author:
Jun ZHANG
;
Hui SUN
;
Haibin ZHANG
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Dipyridamole;
Myocardial ischemia
- From:
Chinese Journal of Ultrasonography
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between acute myocardial ischemia and abnormal motions of left ventricular wall using tissue velocity imaging (TVI) combined with dipyridamole stress echocardiography and evaluate the significance of the new technology in detecting myocardial ischemia. Methods Several grades of constriction on left circumflex coronary artery(LCX) were produced in 13 open-chest canine models. Dipyridamole was added in two steps,first 0.56 mg/kg,then 0.28 mg/kg after four minutes. Views of apical four chambers,two chambers and left ventricular long axis were observed and analyzed. Results In basal condition,the systolic peak velocity(SPV) on different part of wall was various and decreased from cardiac base to apex on each view of long axis. When flow of LCX was decreased 25% and large dosage of dipyridamole was added,the decreasing tendency along the long axis was destructed and SPV of corresponding blood-supply area decreased sharply compared with that of basal condition( P
