Experimental study of acetic acid injection and microwave coagulation in treatment of liver VX_2 tumors of rabbit
- VernacularTitle:醋酸注射及微波凝固治疗兔肝VX_2肿瘤的实验研究
- Author:
Xinghua WANG
;
Jie LI
;
Chenggong LEI
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Liver neoplasms;
Microwave;
Acetic acid
- From:
Chinese Journal of Ultrasonography
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effectiveness of acetic acid injection(AI) and microwave(MW) coagulation in the treatment of rabbits hepatic VX 2 tumors. Methods Eighteen rabbits with VX 2 tumor were divided into two groups randomly,one was treated by precutaneous acetic acid injection,and the other by microwave at laparotomy. Contrast-enhanced ultrasonography (Levovist) was used to assess the therapeutic effect after treatment. Pathologic changes were observed chronologically. Results Anomalo-necrosis areas including tumors and surrounding normal liver tissue were observed after AI,multiple point or sheet necrosis was confirmed by pathology. Long oval-shap coagulated areas were observed after MW,incomplete necrosis after treatment was immediately confirmed by pathology and changed to complete necrosis in two weeks. Conclusions AI is more effective in the treatment of liver tumors,but diffuses easily to normal liver and the necrosis area is not stable. MW thermal field is steady and necrosis area is reliable.
