Injury of Rat Cardiomyocytes Exposed to Nonionizing Radiation and Its Mechanism
- VernacularTitle:非电离辐射对大鼠心肌细胞的损伤及其机制
- Author:
Hua DENG
;
Dewen WANG
;
Ruiyun PENG
- Publication Type:Journal Article
- Keywords:
Radiation,nonionizing;
Myocardium;
Radiation injuries
- From:
Journal of Environment and Health
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the injury of rat cardiomyocytes exposed to nonionizing radiation and its mechanism. Methods Primarily cultured cardiomyocytes were irradiated by 9 GHz 950 mW/cm2 microwave pulse (MWP)and 0～100 MHz 6?104 V/m electromagnetic pulse (EMP)for 72 h respectively ,then a series of apparatus including atom force microscope,laser scanning confocal microscope and flow cytometer were used to detect the changes of cell membrane conformation,structure and function. Results Slower pulsation,abnormal conformation,lower viability ,the significantly increased percentage of apoptosis and necrosis were observed in cardiomyocytes after irradiation by MWP and EMP respectively (P
