Urine tissue polypeptide specific antigen level and its application in the diagnosis of bladder transitional cell cancer
- VernacularTitle:尿组织多肽特异性抗原水平诊断膀胱移行细胞癌的意义
- Author:
Chengbei LIU
;
Wei XU
;
Guijian PANG
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Urine tissue polypeptide specific antigen;
Diagnosis;
Prognosis
- From:
Chinese Journal of Urology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the application and influential factors of urine tissue polypeptide specific antigen(TPS) for early detection and clinical outcome in bladder transitional cell cancers (BTCC). Methods Urine TPS in 76 cases of newly diagnosed BTCC,42 cases of recurrent BTCC,26 cases of postoperative BTCC with normal urine cytology,28 cases of benign bladder diseases,42 normal controls were determined by ELISA.The TPS levels were compared with the cystoscopic results and pathological findings.The relationship between urinary TPS level and the development and prognosis of BTCC was analyzed. Results The urine TPS level was not related to age and sex.The TPS levels in newly diagnosed BTCC group,recurrent BTCC group,postoperative BTCC with normal urine cytology group, bladder benign diseases group and control group were (341?403)U/L,(212?166)U/L,(168?115)U/L,(135?48)U/L and (81?37)U/L,respectively.There was significant difference between each other (all P
