Effect of substance P and epidermal growth factor receptor on the pathogenesis of early psoriasis
- VernacularTitle:P物质和表皮生长因子受体在早期银屑病发病中的作用
- Author:
Wanjuan WANG
;
Baoshan SU
;
Shengshun TAN
;
Junmin WANG
- Publication Type:Journal Article
- Keywords:
substance P;
psoriasis;
epidermal growth factor receptor(EGFR)
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the pathogenesis of substance P (SP) and epidermal growth factor receptor (EGFR) in early psoriasis vulgaris. Methods SP and EGFR were detected in normal skin tissues and psoriatic lesions by radioimmunoassay. Results Expression of SP was significantly enhanced in active and stable psoriasis than in recovery lesions and normal ones (P 0.05). Conclusion SP and EGFR may work together to play a key role in the early pathogenesis of psoriasis.
