Changes of bone mineral density, bone metabolism indices and Vitamin D receptor content in patients with hyperthyroidism
- VernacularTitle:甲亢患者骨密度、骨代谢指标及维生素D受体的变化
- Author:
Xiaoping LIANG
;
Jinli WEN
;
Wenying ZHOU
;
Ziru ZHONG
;
Yaying ZHOU
- Publication Type:Journal Article
- Keywords:
Hyperthyroidism;
Bone mineral density;
Bone metabolism;
Receptor, vitamin D
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Bone mineral density (BMD) of lumbar spines, femoral neck, Ward′s triangle and greater trochanter was lowered, serum calcium, phosphate, alkaline phosphatase and bone Gla-protein levels were raised, and vitamin D receptor (VDR) contents in lymphocyte was lowered in hyperthyroid patients. Both FT 3 and FT 4 were negatively correlated with BMD, suggesting that hyperthyroidism results in high-turnover type of bone loss which causes the abnormalities of bone metabolic indices and VDR content.