Pathological study of rabbit femoral after high-intensity focused ultrasound irradiation in vivo
- VernacularTitle:高强度聚焦超声体外辐照兔股动脉后的病理学观察
- Author:
Qingfeng LI
;
Faqi LI
;
Xueqin YANG
- Publication Type:Journal Article
- Keywords:
High intensity focused ultrasound;
Femoral artery;
Pathology;
Rabbits
- From:
Chinese Journal of Ultrasonography
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To inquire into the hurt-efforts to the rabbit femoral in vivo irradiated by high intensity focused ultrasound(HIFU). Methods Using a HIFU with the operating frequency of 0.8 MHz; the focal distance of 135 mm and the sound-intensity of 8000 W/cm 2. The average interal diameter of the rabbit femoral artery was about 1.1 mm.Thirty rabbits were divided into 3 groups randomly and unilateral-femoral was chosen at random. To observe by using the method of pathology and victorian blue of elastic fibre. Results After irradiation all the endothetial cells of blood vessels of the rabbit peeled off,disappeared and tiny thrombuses were formed in the vessels the core of smooth muscles withered, cell disorder appeared. Conclusions Irradiation by HIFU could cause injury to the rabbit femoral artery, change blood dynamics and produced contribution to the further research on the energy accumulation of the targets in HIFU system.
