Application of MR Perfusion-weighted Imaging in the Evaluation of Therapeutic Effect of Brain Metastases with Gamma Knife
- VernacularTitle:磁共振灌注成像在脑转移瘤伽玛刀疗效评估中的应用
- Author:
Haibo DONG
;
Jiazhong DAI
;
Tianzhen SHEN
;
Haidong XU
;
Zhenhao YU
- Publication Type:Journal Article
- Keywords:
brain;
MRI;
perfusion-weighted imaging;
brain metastases;
gamma knife
- From:
Journal of Practical Radiology
1996;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of MR perfusion-weighted imaging(PWI)in the evaluation of therapeutic effect of brain metastases with gamma knife.Methods Treatment by gamma knife before and after that 3 months or 6 months PWI studies were penformed respectively in 22 patients with brain metastases .Maps of relative regional blood volume(rCBV)and mean transit time(MTT)were obtained.The ratios of rCBV and MTT of lesions were analyzed.Results rCBV of tumors in 22 cases was increased.The ratios of maximum rCBV of the lesions and opposite side were 6.16?3.12 and 1.18?0.17 respectively.The ratios of MTT of the tumors was 1.44?0.53.After gamma knife treatment,9 of 22 cases appeared decreased rCBV,but the ratios of MTT were no changing,of them,3 cases presented cerebral necrosis.13 of 22 cases,the ratios of rCBV were increased in varied degree after treatment by gamma knife,and 6 cases presented brain radionecrosis.Conclusion PWI is a significant method in evaluating the therapeutic effect of brain metastases with gamma knife
