Random amplified polymorphic DNA analysis of candida isolates from oral carriage
- VernacularTitle:口腔念珠菌带菌与感染状态分离菌株的RAPD分析
- Author:
Jufen ZHOU
;
Yanying XU
;
Ruoyu LI
- Publication Type:Journal Article
- Keywords:
Candida albicans;
Random ampified polymorphic DNA;
Mouth
- From:
Journal of Practical Stomatology
1996;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To compare the biotype and genetic similarity between groups of commensal and pathogenic strains of candida species. Methods:Random amplified polymorphic DNA (RAPD) was used to analyse the type of Candida albicans. Results: 12 pathogenic isolates of Candida albicans, 3 commensal isolates of Candida abicans and 3 isolates of pathogenic non-albicans were obtained. The similarity coefficient of albicans with non-albicans was 51.7% by RAPD. Intra-candida similarity coefficient was more than 70%. Both the commensal and pathogenic isolates showed the genetically similar to C. albicans. Intro-isolate DNA polymorphism was observed by RAPD. Conclusion: Both the commensal and pathogenic groups contain a major cluster of genetically similar C. albicans isolates.
