Expression of Nuclear Factor-Kappa B p65 in Gastric Carcinoma and Its Relationship with Vascular Endothelial Growth Factor
- VernacularTitle:胃癌组织中核因子-?Bp65的表达及其与血管内皮生长因子的关系
- Author:
Zhaohui SHI
;
Xinzhong CHANG
;
Xihong JIANG
;
Zhaoting LI
- Publication Type:Journal Article
- Keywords:
Nuclear factor-kappa B Vascular endothelial growth factor Gastric carcinoma Immunohistochemistry
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of nuclear factor-?Bp65 (NF-?Bp65) in gastric carcinoma and its relationship with vascular endothelial growth factor (VEGF). Methods The expression of NF-?Bp65 and VEGF in 56 gastric carcinomas was detected with immunohistochemistry and compared with benign tissues. Results The positive rates of NF-?Bp65 and VEGF in 56 gastric carcinomas were 62.5% and 76.8% respectively,and which were higher than those of gastric mucosal atypical hyperplasia (33.3% and 44.4%) and the normal gastric mucosa(0 and 8.3%) (P0.05). There was positive correlation between NF-?Bp65 and VEGF expression (r=0.36,P
