System Evaluation of Randomized Controlled Trial on Mailuoning Injection in Treating Acute Stage of Ischemic Apoplexy
- VernacularTitle:脉络宁注射液治疗缺血性中风急性期随机对照试验的系统评价
- Author:
Kejian LI
- Publication Type:Journal Article
- Keywords:
Mailuoning Injection(MI);
ischemic brain infarction apoplexy(IBIA);
acute stage;
randomized controlled trial(RTC);
system evaluation
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To make a system evaluation on the therapeutic effect and safety of Mailuoning Injection(MI) in treating acute stage of ischemic brain infarction apoplexy(IBIA).Methods: Literatures about randomized controlled trial (RTC) on MI in treating acute stage of IBIA were collected,and the qualified researches were filtrated.Then made a quality evaluation by Jadad scoring method, and took statistics of the correlated data with the methods of heterogeneity test,Meta-analysis,filler-graph analysis and sensitivity analysis etc.Results: There were eight items accorded with bringing into standard.Then the methodology quality of each articles were evaluated adopting Jadad scoring standard,and the trials each get one score,belonging to low-quality literatures.The analytic results of Meta-analysis showed that compared with blank control group,the total effective rate comparison relative risk(RR) to merge equaled 1.19,99% confidence interval(CI) was(1.09,1.30),the case-fatality rate(CFR) comparison relative risk(RR) equaled 0.93,99% confidence interval(CI) was(0.02,36.07). Conclusion: This system evaluation demonstrated that MI was good for treating acute stage of IBIA,and no serious adverse reactions.
