Association between Helicobacter pylori infection and expression of cyclooxygenase-2 in gastric mucosa
- VernacularTitle:幽门螺杆菌感染与胃黏膜环氧化酶-2表达的关系
- Author:
Hongxia LI
;
Zhengjun SONG
;
Rong DUAN
- Publication Type:Journal Article
- Keywords:
cyclooxygenase-2;
Helicobacter pylori;
chron ic gastritis
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of H.pylori infection on cyclooxygenase-2(COX-2)expression in gastric antral mucosa. Methods The expression of COX-2 in 20 patients with H.py lori -infected chronic gastritis and in 14 with uninfected chronic gastritis w ere investigated by immunohistochemical method. The expressions of COX-2 in the antral mucosa were compared before and after H.pylori eradication. Results The mean percentage of the cells stained with COX-2 was s ignificantly higher in H.pylori -infected mucosa than that in uninfected mucosa ( P
