ERYTHROCYTE MEMBRANE CARBOHYDRATES, LIPIDS AND Ca~(2+)-Mg~(2+) ATPase IN DUCHENNE MUSCULAR DYSTROPHY
- VernacularTitle:Duchenne型肌营养不良红细胞膜糖、脂质及Ca~(2+)-Mg~(2+)ATP酶的变化
- Author:
Yaomei WEI
- Publication Type:Journal Article
- Keywords:
Duchenne muscular dystrophy;
erythrocyte membrane;
membrane lipids, siali cacid, Ca2+ -Mg2+ ATPase
- From:
Academic Journal of Second Military Medical University
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The carbohydrate and lipid contents and Ca2+-Mg2+ ATPase activity of erythrocyte membrane were studied in 10 patients with DMD. The results demonstrated that the sialic acid content was markedly decreased, and the neutral sugar content normal. The cholesterol was significantly increased, but the phospholipids unchanged, resulting in a significantly reduced P/C ratio. The activity of Ca2+-Mg2+ ATPase elevated markedly. The study suggests that the erythrocyte membranes with DMD are altered both in composition and function.
