Assessment of interstitial fibrosis in myocardium of advanced age spontaneous hypertension rats by acoustic densitometry
- VernacularTitle:声学密度技术评价高龄高血压大鼠心肌间质纤维化
- Author:
Heng CAI
;
Yun ZHANG
;
Mei ZHANG
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Hypertension;
Rats;
Myocardial diseases
- From:
Chinese Journal of Ultrasonography
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the reliability to asses s interstitial fibrosis in myocardium of advanced age spontaneous hypertension rats(SHR) by acoustic densitometry. MethodsFifteen 20-month-old spontanous hypertension rats and fifteen age matched Wistar Kyoto(WKY) as control group were included. Ultrasonic backscatter parameters were acquired at interventricular septum, left ventricular posterior wall, left ventricular lateral wall. Normalized values of integrated backscatter of left ventricular lateral wall were compared with results by stereological approach under eletronic and light microscope. Results Compared with control group, SHR group showed different integrated backscatter at interventricular septum, left ventricular posterior wall and left ventricular lateral wall(P
