Experimental study of true precocious puberty model in female rats
- VernacularTitle:雌性大鼠真性性早熟发生模型的实验研究
- Author:
Jian PAN
;
Hailang LI
;
Yinan ZHENG
- Publication Type:Journal Article
- Keywords:
Puberty, precocious;
Rats, Sprague-Dawley;
Excitatory amino acids;
N-methyl-DL-aspartate
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The precocious puberty in female rats were induced by subcutaneous injection of N-methyl-DL-aspartate (NMA). The female rats with induced precocious puberty showed the same sexual feature as the rats that had normal puberty. NMA plays its role at the level of hypothalamus. Subcutaneous injection of NMA is an effective means to induce true precocious puberty in female rats.
