EFFECTS OF IRON EFICIENCY OF COCHLEAR STRUCTURE AND FUNCTIONS IN RATS
- VernacularTitle:缺铁对大鼠耳蜗结构与功能的影响
- Author:
Aihua SUN
- Publication Type:Journal Article
- Keywords:
iron-deficiency auditory brain-stem response electrocochliogram cochlear pathology rats
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
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Abstract:
To investigate the effects of iron deficiency on cochlear structure and functions, an auditory electrophysiological and histopathological study was conducted in the rats which were fed with either a basic Fe-deficient diet or a standard diet.It was found in iron-deficient rats that the incidence of threshold elevation (more than 15 dB) in both auditory brain-stem response and electrocochleogram-N1Was 31.85%, and cochlear histopathological changes were stria atrophy and reduction of spiral ganglion cells. No change was found in the controls.These findings suggest that iron deficiency could be a direct cause of sensorineural hearing loss, or could provide a pathological basis for cochlear deafness.
