THE EFFECT OF RIBOFLAVIN ON THE PREVENTION OF TERATOGENESIS
- VernacularTitle:核黄素阻抑致畸作用的效果观察
- Author:
Chengde LING
;
Liying YANG
;
Zumin NI
- Publication Type:Journal Article
- Keywords:
riboflavin teratogenesis
- From:
Acta Nutrimenta Sinica
1956;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
In order to study the new function of riboflavin, the experiments of ri-boflavin on the prevention of teratogenesis were conducted. The experimental rats were divided into four groups A,B,C,D. A served as a control group, B,C,D, were given 50?g, 250ng and 1000?g of riboflavin respectively for one week intragastrically prior to the study. After pregnancy, all rats including controls were given teratogenic pesticide Dikushuang 0.75mg/kgbw for contaminaton intragastrically, riboflavin being given continually as before, to observe the effects on body weight growth and hemoglobin level of pregnant rats. The following parameters were measured: the reproduction of pregnant rats, the development of fetus and the teratogenic activity of fetus after animals were killed. The experimental results showed that the average body weight gain in the each dose groups of riboflavin were higher than the control group, but the difference was not significant. The hemoglobin levels at various experimental times were less significant among the groups.The rates of the resorption and the living fetus in 250?g and 1000?g groups were significantly lower than the control (P
