PATHOLOGICAL OBSERVATIONS ON THE ENZYME-LABELING IMMUNO-FETOPROTEIN IN HUMAN NONCIRRHOTIC LIVER CANCER AND PERI-CANCER TISSUE
- VernacularTitle:无肝硬化肝癌和宿主肝甲胎蛋白免疫酶标记定位及其病理形态学研究
- Author:
Wenzhao TAO
- Publication Type:Journal Article
- Keywords:
immunoenyme technics alpha fetorotein neoplasms liver cirrhosis
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
pathological observations on 32 surgical cases of noncirrhotic hepatocellular carcin-oma(NCH)were made. 12 surgical cases of cirrhotic hepatocellular carcinoma(CH) were taken as control. Routine fixed method were made by immunoperoxidase staining for AFP.The results were as follows. (1)The positive rate of NCH group host liver is somewhat higher than those of cancer tissue.AFP positive meterials were also observated in 3 cases with proliferative bile-duct epithelium, as compared with CH group,the AFP positive materials distributed in the tissue are similar to those in she cells.The differences of the AFP intensity and the positive rate of NCH group host liver are less than that of CH group.(2)In NCH group, the rate of positive cases of hepatis B is 53.13 %.it is markedly higher than that in 28.13% of orcein negative hepatitiis. (3)The AFP distributing in the cancer tissue and cancer cells were similar to those in the host liver tissue.but much more distributing in the cancer peri-trabecula.(4)It suggested that the review study by routine fixztion and staining immunoperxidase method for AFP is available progressed.
