THE EXPERIMENTAL RESEARCH OF TREATING THE LIVER CANCER OF MICE USING INVASIONAL MICROWAVE
- VernacularTitle:大鼠肝癌侵入性微波治疗实验研究
- Author:
Hongkai HU
- Publication Type:Journal Article
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
This paper describes an animal experiment in which the microwave was used to treat hepatic cancer by inserting a coaxial monoantenna into the tumor to induce hyperthermia The experimental results showed that the carcinoma 1 cm in diameter could be killed completely if the central ternperature remains at 42-45℃ for 5 minutes.The animals with such a treatment have been followed up for 90 days and no reoccurrence was ever found. The cancer tissue being treated was replaced by slight scar.The mice of the control group survived only 31 days averagely.We found that the liver function was affected to some extent by microwave radiation.The value of the scrum enzymes such as GPT and PHI etc decreased apparently.Serum level of these enzymes began to increase in two hours after the treatment and reached its height within 24 hours.On the seventh day their concentration returned to normal. The conversional rate of the lymphocytes which significantly fell was 6 times lower than the original one even after two weeks of the treatment. It is suggested that the microwave can directly act on the liver, the function of the immunity is obviously disturbed and the recovery is slow. In order to avoid the postoperative colliquativs necrosis and abscess, antibiotics must be applied. Prevention of infection and complications will bring about a smooth procedure of the treatment.
