Analysis of HLA-DR expression in relation to the development of oral squamous cell carcinoma
- VernacularTitle:人口腔鳞癌演变过程中HLA-DR表达改变的研究
- Author:
Shaoping ZHANG
;
Longjiang LI
;
Xin HUANG
- Publication Type:Journal Article
- Keywords:
HLA DR antigens;
Mouth;
Squamous cell neoplasms;
I mmunohistochemistry
- From:
Journal of Practical Stomatology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe HLA DR expression in different s tages of oral squamous cell carcinoma (OSCC) and to study the clinic significan ce of the abnormal HLA DR expression in primary OSCC. Method: HLA DR expression was detected by immunohistochemistry method in 26 cas es of histologically normal oral epithelia, 8 leukoplakia, 32 primary focuses an d 12 metastasis focuses of OSCC. Results: HLA DR express ion in primary OSCC focuses was significantly higher than that in normal epithel ium( P 0.05). Conclusion: Although HLA DR expression is frequently obs erved in the development of OSCCs, it can not be regarded as one of the indepen dent prognosis factors.
