Expression of BMP2 and IGF1 in the periodontium of experimental regeneration a ffected by slow-releasing Shuanghuangbu strip
- VernacularTitle:双黄补缓释药条对实验性牙周组织再生中BMP2和IGF1表达的影响
- Author:
Yanzhi XU
;
Shijie WANG
;
Dongmei ZHANG
- Publication Type:Journal Article
- Keywords:
Traditional chinese medicine and pharmacy;
Alveol ar bone loss;
Bone morphogenetic proteins;
Insulin like growth factor 1
- From:
Journal of Practical Stomatology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of Shuanghuangbu slow releasing strip (SRSS) on the expression of BMP2 and IGF1 in the experimental regeneration of periodontium. Methods:Periodontal defects were surgically made around the second incisor and the ca nine in four beagle dogs .32 defects were randomly divided into experimental gr oup and control group with 16 defects in each group. SRSS was applied to the e xperimental group and no disposition to periodontal defect in the control group. Two teeth of each dog were randomly chosen as the natural controls.Specimens we re respectively obtained one month and three months after operation. BMP2 and I GF1 were quantitatively analyzed by immunohistochemistry. Results:The positive rate of BMP2 and IGF1 in experimental group were higher t han those in the control( P
