The distribution and degradation of albumin microspheres injected into jugular external artery
- VernacularTitle:白蛋白微球经颈外动脉灌注后的体内分布及降解速度
- Author:
Chengge HUA
;
Yuming WEN
;
Fenghua FU
- Publication Type:Journal Article
- Keywords:
Albumin microspheres (AMS);
Embolize therapy;
Arterial infu sion
- From:
Journal of Practical Stomatology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the distribution and degradatio n of albumin microspheres (AMS) with average diameter of 56.3 ?m injected into jugular external artery.Methods: 125 I labeled AMS we re injected into rabbit's jugular external artery. The radioactive amount of loc al tissue and internal organs was measured. 760 ml/L urografin angiography was e mployed to observe the re opening of embolized vessels after AMS infusion of e xternal jugular artery in 5 dogs. Results: The AMS was mai nly concentrated in the target area (92.23%) after injection. The micro artery was obviously embolized by AMS and re opened in 7～9 days. Conclusio n : The AMS can be used as the drug bearer with delayed releasing eff ection.
