The clinical evaluation on chemo-endocrine therapy for advanced gastric carcinoma
- VernacularTitle:进展期胃癌患者化学内分泌治疗的临床评价
- Author:
Xinhan ZHAO
;
Tianjie QIN
;
Juxiang XIAO
;
Xiaojuan ZHOU
;
Shanxi LIU
- Publication Type:Journal Article
- Keywords:
chemotherapy;
chemo-endocrine therapy;
gastric neoplasm
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of chemo-endocrine therapy on gastric carcinoma (GC). Methods Cancerous tissues from 95 patients with primary GC were examined for the presence of estrogen receptor (ER) and progesterone receptor (PgR). Afterwards, 64 GC patients with recurrent or metastatic conditions were randomly divided into two groups: chemotherapy group and chemo-endocrine therapy group. Results A total of 34.38% ER positive and 16.30% PgR positive rates were found. For ER positive patients, the use of tamoxifen-EAP regimens was more effective than that of EAP alone (P