Expression of cyclooxygenase-2,vascular endothelial growth factor and their prognostic significance in gastric carcinoma
- VernacularTitle:COX-2、VEGF在胃癌中的表达及其预后意义
- Author:
Hai SHI
;
Jianming XU
;
Naizhong HU
- Publication Type:Journal Article
- Keywords:
gastric neoplasms;
cyclooxygenase-2;
vascular endothelial growth factor;
prognosis;
immunohistochemistry
- From:China Oncology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To investigate the relationship between expression of COX-2,VEGF in gastric carcinoma and its prognostic significance.Methods:281 patients with early and middle stage of gastric carcinoma were followed up. Expression of COX-2 and VEGF was examined by immunohistochemistry in 232 archival paraffinembedded tissue specimens.Results:The MVD value was much higher in COX-2(+) group and VEGF(+) group than that in COX-2(-) group and VEGF(-) group ( P
