A study on blood lipids and apolipoproteins in type 2 diabetic patients and their normoglycemic first-degree relatives in Chinese type 2 diabetic pedigrees
- VernacularTitle:中国人2型糖尿病家系中糖尿病患者及其一级亲属血脂和载脂蛋白的研究
- Author:
Lingchuan HAN
;
Haoming TIAN
;
Yan REN
;
Xiujun LI
;
Jianan WANG
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus, non-insulin-dependent;
Pedigree;
First-degree relative;
Apolipoproteins
- From:
Chinese Journal of Endocrinology and Metabolism
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of changes in lipids and apolipoproteins (Apo) in type 2 diabetic patients and their normoglycemic first-degree relatives (NFDR). Methods Triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), ApoAⅠ, ApoB_ 100 , ApoCⅢ and ApoE were determined in 62 type 2 diabetic patients and 67 NFDR from 29 Chinese type 2 diabetic pedigrees as well as 45 normoglycemic controls without family history of diabetes (NC) in Chengdu city, China. Results (1)TG level was higher in type 2 diabetic patients 〔(1.85?1.31)mmol/L〕 as compared with those in NFDR 〔(1.39?0.91)mmol/L〕 and NC 〔(0.92?0.45)mmol/L〕, and TG level in NFDR was higher as compared with that in NC (all P
