Relationship between aldose reductase gene expression in peripheral blood mononuclear cells and the risk of diabetic nephropathy in type 2 diabetic patients
- VernacularTitle:2型糖尿病患者外周血单个核细胞中醛糖还原酶mRNA水平与糖尿病肾病危险性的关系
- Author:
Minhui HE
;
Hong LI
;
Chengjiang LI
- Publication Type:Journal Article
- Keywords:
Aldose reductase;
Diabetes mellitus, non-insulin dependent;
Diabetic nephropathies;
Urinary albumin excretion rate
- From:
Chinese Journal of Endocrinology and Metabolism
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Aldose reductase (AR) mRNA level in peripheral blood mononuclear cells was assayed by RT-PCR. There was a positive correlation between PBMC AR mRNA level and urinary albumin excretion rate in type 2 diabetic patients. The result suggests that AR activity is related to the pathogenesis of diabetic nephropathy.
