Expressions of IL-6 receptor subunit gp80 and gp130 genes in bone marrow of osteoporotic rat
- VernacularTitle:骨质疏松大鼠骨髓白细胞介素6受体亚单位gp80和gp130基因的表达
- Author:
Jiang LUO
;
Xiuzhen ZHANG
- Publication Type:Journal Article
- Keywords:
Osteoporosis;
Receptors, interleukin-6;
Rats, Sprague-Dawley
- From:
Chinese Journal of Endocrinology and Metabolism
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Gene expressions of interleukin-6 receptor subunit gp130 and gp80 were investigated by competitive RT-PCR in the rat model of osteoporosis. A significant increase in expressions of gp130 and gp80 was found in bone marrow of osteoporotic rat, this change may be a possible mechanism in osteoporosis due to loss of estrogen.