Change of the serum IL-18, sFas and sFasL levels in patients with severe burn and their relationships
- VernacularTitle:严重烧伤患者血清IL-18、sFas和sFasL水平的变化规律及其相关性研究
- Author:
Xiaodong CHEN
;
Qiong JIANG
;
Boyu WU
- Publication Type:Journal Article
- Keywords:
Burn;
Interleukin-18;
Fas;
FasL
- From:
Chinese Journal of Immunology
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the change of the serum IL-18, sFas and sFasL levels in patients with severe burn and its correlation with the morbid condition and outcome Methods:Thirty patients, including three fatal cases, had burn with a total burn surface area (TBSA) of 30% or more 45 healthy volunteers were as control group The serum IL-18, sFas and sFasL levels were measured by enzyme-linked immunosorbent assay (ELISA) at various time points ( 1, 3, 5, 7, 14, 21, 28 and 35 days) burn later Results:Compared with control group, the levels of IL-18, sFas and sFasL of patients increased significantly after burn (P
