Clinic study to evaluate left ventricular chamber stiffness by catherization and simultaneous echocardiography
- VernacularTitle:超声心动图-心导管同步血流动力学技术评价左心室心腔僵硬度的临床研究
- Author:
Ming ZHONG
;
Yun ZHANG
;
Wei ZHANG
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Heart catherization;
Hemodynamics;
Left ventricular pressure-volume loop;
Left ventricular chamber stiffness
- From:
Chinese Journal of Ultrasonography
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the method of depict ing the left ventricular (LV) pressure-volume loop automatically by computer which incorporates LV catherization simultaneous with LV acoustic quantification echocardiography and to assess echocardiography non-invasive evaluation LV chamber stiffness. Methods Thirteen patients with hypertrophic cardiomyopathy (HCM) underwent LV catherization simultaneously with echocardiography. LV pressure and volume curves were sent to computer, and LV pressure-volume loop was depicted automatically and modulus of LV chamber stiffness (Kc) was obtained. Pulsed Doppler echocardiography of mitral intraventricular flows was obtained in patients with HCM. Results Patients with HCM had significantly higher Kc obtained from LV pressure-volume loop ( 0.43 ? 0.11 vs 0.27 ). R-E 3/R-E 0, (R-E 2)-(R-E 1), (R-A 3)-(R-A 2) were correlated to Kc(r= 0.61 , 0.57 , 0.58 ,respectively). Conclusions This method provides a simple and reliable technique for automatically tracing pressure-volume loop and should facilitate further investigation of the left ventricular diastolic function in clinical practice. R-E 3/ R-E 0, (R-E 2)-(R-E 1), (R-A 3)-(R-A 2) offer new non-invasive indices in evaluating LV chamber stiffness.