Clinical study of age factor in cryptorchidism and optimal timing of cryptorchid opexy in children
- VernacularTitle:隐睾儿童手术近期疗效及手术时机的探讨
- Author:
Guosheng YANG
- Publication Type:Journal Article
- Keywords:
Cryptochidism;
Operation timing;
Cryptorc hiopexy
- From:
Chinese Journal of Urology
2000;0(12):-
- CountryChina
- Language:Chinese
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Abstract:
ObjectiveTo study the age factor in cryp to rchidism in children,the optimal timing of cryptorchidopexy and short-term effe ct following the operation.MethodsThe levels of serum epidermal growth factor(EGF),testosterone(T),5?-dihydrotestosterone (5?-DHT) ,estradiol(E 2),luteinizing hormone(LH),follicle-stimulating hormone(FSH) and prolactin(PRL) were measured with radioimmunoassay (RIA) in 88 children with cry ptorchidism before and after operation,and the expression of EGF receptor(EGF-R ) and androgen receptor(AR) was determined using immunohistochemical technique. ResultsAmong the 88 children with cryptorchidism,the i mpalpable testes were more common in 2-to 4-year group (9/24,37.5%),whereas th e extracanalicular testes were more common in 10-to 14-year group (20/24, 81. 8 %).The difference was significant ( P
