Modified simultaneous kidney-pancreaticoduodenal transplantation with enteric drainage of exocrine pancreatic secretions(report of 2 cases)
- VernacularTitle:改良式胰液肠腔引流胰十二指肠及肾一期联合移植(附二例报告)
- Author:
Lixin YU
;
Bing YAO
;
Wenfeng DENG
- Publication Type:Journal Article
- Keywords:
Pancreas;
Kidney;
Diabetes mellitus;
Insulin-dependent;
Transplantation
- From:
Chinese Journal of Urology
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the modified clinical technique and experience of simultaneous kidney-pancreatic transplantation (SKPT) with enteric drainage(ED). Methods Two patients with insulin-dependent diabetes mellitus and end-stage renal disease underwent SKPT with enteric drainage of exocrine secretions.The patients were treated with quadruple therapy including antithymocyte globulin (ATG) induction therapy,prednisone,FK506,and Mycophenolate-Mofetil(MMF), as maintenance immunosuppression. Results The two patients became insulin-independent after treated by small dose insulin for 5～10 days and Scr,BUN became normal 3～5 days after the operation.Until now all the grafts of the patients functioned well. Conclusions ED-SKPT is more effective than simultaneous kidney-pancreatic transplantation with bladder drainage (BD-SKPT).ED-SKPT is an effective method for treating type Ⅰdiabetes mellitus with uremia.Finer allograft and nicer HLA-typing can decrease complications.
