Comparison between nuclear matrix protein 22 (NMP 22) test and voided urine cytology for detection of bladder cancer
- VernacularTitle:核基质蛋白22检测与尿脱落细胞学检查在膀胱癌诊断中的价值
- Author:
Ran YOU
;
Weidong SONG
;
Yi DING
- Publication Type:Journal Article
- Keywords:
Bladder cancer;
Nuclear matrix protein;
Urine cytology
- From:
Chinese Journal of Urology
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the sensitivity and specificity of NMP 22 test with voided urine cytology in detection of bladder cancer and to evaluate their clinical values. Methods For 155 patients suspected with bladder cancer NMP 22 and cytology were conducted in the same voided urine samples.Of them 95 patients with bladder transitional cell carcinoma were confirmed histologically.The sensitivity and specificity of NMP 22 and urine cytology were analyzed.60 patients without bladder cancer were selected as control. Results The overall sensitivity and specificity of NMP 22 test were 65.3% and 70.0%,respectively,those of urine cytology were 43.2% and 83.3%,respectively.There was no significant difference between the specificity of urine cytology and that of NMP 22 test;however,NMP 22 was significantly more sensitive than urine cytology in detection of any stages and grades of bladder cancer(P
