The association of platelet-derived endothelial cell growth factor with bladder transitional cell carcinoma
- VernacularTitle:血小板源性内皮细胞生长因子与膀胱移行细胞癌的相关性研究
- Author:
Yichun ZHENG
;
Wei DING
;
Songliang CAI
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Carcinoma,transitional cell;
Platelet-deriver endothelial cell growth factor;
Vascular endothelial growth factor;
Microvessel density
- From:
Chinese Journal of Urology
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of clinical and pathological characteristics of bladder transitional cell carcinoma(BTCC) with platelet-derived endothelial cell growth factor (PD-ECGF). Methods Expression of PD-ECGF,VEGF and MVD were examined in the specimens of 52 cases of BTCC by Envision immunohistochemical staining.All the 52 cases were followed up via interview for a period of 5 years. Results Of the 52 cases 50 provided complete relevant data.The 5-year postoperative tumor-free survival rate was 42.9%(21/49) and overall survival rate was 78.0%(39/50).The positive expression rate of PD-ECGF in G 1 tumors was 17.6%(3/17);in G 2,59.3%(16/27) and in G 3,87.5%(7/8)(P
