Treatment of detrusor-external sphincter dyssynergia caused by spinal cord injury with transperineal injection of botulin A toxin
- VernacularTitle:经会阴肉毒素注射治疗脊髓损伤所致逼尿肌外括约肌不协调
- Author:
Jing SHI
;
Guochang ZHOU
- Publication Type:Journal Article
- Keywords:
Spinal cord injuries;
Urination disorder;
Detrusor;
External sphincter;
Botulinum toxins
- From:
Chinese Journal of Urology
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of transperineal injection of botulin A toxin on patients with detrusor-external sphincter dyssynergia caused by spinal cord injury. Methods Transperineal injection of botulin A toxin were performed in 6 patients with spinal cord injury (3 with cervical spinal cord injury and 3 with thoraco-lumbar spinal cord injury) complicated by detrusor-external sphincter dyssynergia.55 U of botulin A toxin was injected twice separately. The interval between 2 injections was 3 days.Before treatment, the residual volume of urine after voiding was determined and the maximum urethral pressure was measured by urodynamic testing.One month after treatment the examination mentioned above was repeated. Results The decrease in residual volume of urine was (133.3?70.9)ml.The decrease in maximum urethral pressure was (35.4?25.8)cmH 2O(both P
