Value of urinary cytokeratin 8 and 18 as a diagnostic marker for transitional cell carcinoma
- VernacularTitle:尿细胞角蛋白检测在诊断尿路移行细胞癌中的价值
- Author:
Tao LI
;
Zifu CHEN
;
Chengdong LIN
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Keratin;
Diagnosis,laboratory
- From:
Chinese Journal of Urology
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the clinical efficacy of cytokeratin 8 and 18 as a novel urine marker for transitional cell carcinoma (TCC) of urinary tract. Methods Urinary concentrations of cytokeratin 8 and 18 were determined by an enzyme-linked immunosorbent assay (ELISA) in 52 cases of TCC and 86 cases of other urological conditions. Results The urinary values of cytokeratin 8 and 18 in the TCC patients (mean 34.8 ?g/l) were significantly higher than those in the patients without TCC (mean 9.4 ?g/l)(P
