Essential role of thyroid hormones in brain developm ent
- VernacularTitle:甲状腺激素对脑发育的重要影响
- Author:
Qing SU
;
Min LUO
- Publication Type:Journal Article
- Keywords:
Thyroid hormones;
Brain;
Development;
H ypothyroidism
- From:
Chinese Journal of Endocrinology and Metabolism
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Thyroid hormones (TH) play an imp or tant role in the development and maturity of the mammalian brain. Maternal TH de ficiency, even subclinical hypothyroidism, leads to poor neurodevelopment of the fetus. Screening of pregnant women for hypothyroidism is recommended. Identific ation of the TH-responsive genes in the developing brain and investigation on t heir functions are helpful to provide insights into the molecular mechanisms by which TH influence brain development.